Regenerating Craniofacial Dental Defects With Calcium Phosphate Cement Scaffolds: Current Status and Innovative Scope Review

The management and treatment of dental craniofacial injuries have continued to evolve throughout the last several decades. Limitations with autograft, allograft, synthetics created need for more advanced approaches in tissue engineering. Calcium phosphate cements (CPC) are frequently used repair bone defects. Since their discovery 1980s, extensive research has been conducted improve properties, emerging evidence supports increased application This review focuses on up-to-date performance calcium cement scaffolds upcoming promising regeneration strategies. First, we summarized barriers encountered CPC scaffold development. Second, compiled most up date vitro vivo literature. Then, a systematic search scientific articles MEDLINE EMBASE screen related studies. Lastly, revealed current developments effectively design track enhanced viability therapeutic efficacy overcome limitations perspectives. Finally, presented timely opportune article focusing significant potential regeneration, which will be discussed thoroughly. offers multiple capabilities that may considered toward oral defects, expecting future outlook nanotechnology performance.